Conference Program

The program is now available as PDF
(you will receive a booklet with these contents onsite, please DO NOT print)

Saturday, January 20

Registration desk open from 16.00 

KEYNOTE LECTURE AND WELCOME RECEPTION
18.00 Thomas Boehm Evolutionary novelties in vertebrate adaptive immune systems
19.00 Mix and Meet - Fingerfood will be served
     

Sunday, January 21

 

LYMPHOCYTE DEVELOPMENT AND MALIGNANCIES
09.00 Ellen Robey A multi-omics approach to dissecting T cell fate in the thymus
09.30 Andreas Krueger High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo
09.45 Robin Thiele Constrained B-cell development promotes malignant transformation
10.00 Carlota Farre Dias Using sequential mutagenesis to model human multiple myeloma subgroups in mice
10.15 Coffee Break  

 

HUMORAL IMMUNITY
10.45 Carola Vinuesa Signals driving pathogenic B cells in autoimmunity
11.15 Gabriel Victora B cell selection in germinal centres
11.45 Louise Webb Rejuvenation of the Germinal Center Reaction and Affinity Maturation Following Depletion of T Follicular Helper Cells
12.00 Mirela Kuka IFNγ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses
12:15 Lunch Break  

 

CONTROL OF GENE EXPRESSION AND PROTEIN FUNCTION
14.00 Chunaram Choudhary Lysine acetylation in gene regulation
14.30 Martin Turner RNA binding proteins limiting T cell differentiation and function
15.00 Borja Jimenez Lasheras Neddylation as a relevant agent in metabolism and antitumor capacity of CD8+ T cells
15.15 Daniel Greenwood Mapping the heterogeneity of NF-kB response in primary human immune cells with deep-learning assisted high content microscopy
15.30 Coffee Break  

 

T CELL ACTIVATION
16.00 Romain Roncagalli Insights into the molecular mechanisms encoding TCR ligand discrimination
16.30 Alexander Leithner A second-generation supported lipid bilayer system to study the effects of ligand lateral mobility on T cell activation
16.45 Katarzyna Jobin Post priming long-term T cell interaction niches scale CD8 and CAR Teff formation
     

Monday, January 22

 

AT THE CROSSROADS OF INNATE AND ADAPTIVE IMMUNITY
09.00 Taras Kreslavskiy Unusual specificities of γδ T cells
09.30 Chiara Romagnani Adaptive features of NK cells
10.00 Immo Prinz Resident  γδ and αβ T cells in human lung and associated lymph nodes adapt into complementary regulatory and cytotoxic phenotypes
10.15 Georg Gasteiger Differentiation of innate and adaptive tissue-resident lymphocytes during ontogeny, infection and allergy
10.30 Coffee Break  
11.00 Gleb Turchinovich Power of two: new binary Cre mouse model specifically targeting type 3 Innate Lymphoid Cells
11.15 Julie Ribot IL-17 regulates peripheral nerve regeneration
11:30 Burkhard Becher Cytokines in inflammation and cancer
12:00 Lunch Break  

 

TRANSCRIPTIONAL CONTROL OF IMMUNE CELL FUNCTION
17.00 Ananda Goldrath Transcriptional programming of T cell tissue immunity in space and time
17.30 Ari Glasner Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies
17.45 Carmen Gerlach CD8+ T cell differentiation and activation represent distinct axes of diversification
18.00 Poster Session I – Fingerfood will be served
     

Tuesday, January 23

 

MYELOID CELL BIOLOGY
09.00 Caetano Reis e Sousa DaNgeRous necrophagy, coprophagy and immunity to cancer
09.30 Michael Sixt Coordination of mechanical forces in migrating leukocytes
10.00 Barbara Schraml Identification of unique RORγt expressing antigen presenting cells conserved across tissues and species
10.15 Michael Kern Host intestinal perivascular macrophages protect against murine acute graft-versus-host disease via PD-L1
10.30 Coffee Break  

 

TOLERANCE AND AUTOIMMUNITY
11.00 Adrian Erlebacher Mechanisms of fetomaternal tolerance
11.30 Andrew Koh Thymic epithelia destabilize chromatin via p53 repression to amplify transcriptional noise for AIRE-mediated immune tolerance
11.45 Stefano Angiari Coenzyme A fueling with pantethine limits autoreactive T cell pathogenicity in experimental neuroinflammation
12.00 Lunch Break  

 

IMMUNITY AND AGING
17.00 Donna Farber Tissue and age as determinants for human immunity
17.30 Maria Mittelbrunn Decoding the contribution of the immune system to aging
18.00 Poster Session II – Fingerfood will be served
     

Wednesday, January 24

 

HUMAN IMMUNOLOGY
09.00 Muzlifah Haniffa Decoding the developing human immune system
09.30 Alexander Scheffold Exhausted autoreactive T cells in human autoimmunity
10.00 Georg Stary Tissue-resident T cells as guardians of cutaneous immunity
10.30 Coffee Break  

 

CANCER IMMUNOLOGY
11.00 Susan Kaech Stressing out our immune system in cancer
11.30 Axel Kallies Differentiation and function of cytotoxic T cells in chronic infection and cancer
12.00 Patrizia Stoitzner Tumor-targeted therapy with BRAF-inhibitor remodels the myeloid landscape to promote tumor immunity in melanoma
12.15 Lydia Dyck Analysis of mechanisms promoting T cell tolerance against autochthonous cancer in aged mice
12:30 Lunch Break  

 

IMMUNITY IN TISSUES
14.00 Matteo Iannacone Immune surveillance of the liver
14.30 Nicole Joller The co-inhibitory receptor TIGIT promotes tissue protection and repair
15.00 Coffee Break  
15.30 Jan Dobes Segmented filamentous bacteria-induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover
15.15 Anneli Peters T:B cell cooperation in ectopic lymphoid follicles in CNS autoimmunity
16.00 Marion Pepper Memory T cells in tissues
19.00 Farewell Dinner